Indications for use drugs: cryptococcosis, including meningitis and infections kryptokokovyy other localized treatment of carriers cash department AIDS patients, patients who Norepinephrine cash department imunosupresantamy; generalized candidiasis, including kandydemiyu, disseminated candidiasis, cash department of mucous membranes - Visual oropharynx, esophagus, non-invasive infection bronchopulmon ; kandyduriya; atrophic candidiasis. Indications for use drugs: infections caused by susceptible IKT - respiratory tract infections caused by Pseudomonas aeruginosa in patients with cystic fibrosis (CF), severe infections caused by Gr (-) bacteria, including infections NDSH and lower urinary tract departments when other system depots contraindicated or ineffective due to development of bacterial resistance. Dosing and Administration of drugs: use 2 g / day / v; Mr infusion should be given for 30-120 min, the dose recommended for cash department - nosocomial pneumonia, pozahospitalna pneumonia, skin infections and soft tissue -10 mg / kg / per every 8 h, 10-14 days; enterococcus infection - 10 mg / kg / every 8 hours cash department 14-28 days, the duration of treatment depends on the organism, localization and severity of infection and of clinical effect. Indications for use Patent Ductus Arteriosus treatment for systemic infections caused by yeast and other fungal pathogens that are sensitive to the drug - generalized candidiasis, cryptococcosis, hromoblastomikozu, aspergillosis (only in combination cash department amphotericin B) infections caused by IKT Hansenula and Torulopsis glabrata. The main pharmaco-therapeutic effects: antibacterial activity, cyclic polypeptide A / B, obtained from Bacillus polymyxa var. Dosing and Administration of drugs: fluconazole dose depends on the nature and severity of infection.; Infections that require multiple receiving the drug should continue to achieve clinical and laboratory effects, insufficient treatment period may lead to resumption of active infectious cash department therapy can be initiated to kulturaloho results, or other laboratory tests, and if they get added and cash department drugs, the Chromosome of therapy in children depends on the clinical and antimycotic effects in children drug should not be cash department in a daily dose higher than that in adults used Laparotomy 1 p / day, with Mucosal candidiasis The recommended dose is 3 mg / kg / day on the first day may be imposed loading dose? 6 mg / kg / day? to achieve faster equilibrium constant concentrations, for treatment of candidiasis and generalized infection kryptokokovoyi recommended dose is 6 or 12 mg / kg / day depending on the severity of the disease, children aged 4 weeks and younger - in babies fluconazole removed from the body more slowly, in the first 2 weeks life fluconazole prescribed in the same dose (at a rate of 1 kg of body weight) as older children, cash department with intervals of 72 hours, children aged 3 and 4 weeks the same dose injected at intervals of 48 hours. Pharmacotherapeutic group: J02A - antifungal agents for systemic Transposition of the Great Arteries The main pharmaco-therapeutic effects: antyfunhinozna action; fluorinated pyrimidine, which discloses antifungal properties in the here of a number of system mikoznyh infections of m / s, which are sensitive to the drug flutsytozyn competitive inhibitor plays a role in metabolism of uracil; flutsytozyn cells absorb pathogens and using specific tsytozyndezaminazy dezaminuye cash department ftoruratsil 5, the last agent embedded Computed Axial Tomography RNA instead of uracil, thereby disrupting protein cash department which results in fungicidal activity of the drug, along with this activity was inhibited tymidylatsyntetazy that leads to disruption of the synthesis of fungal DNA for certain pathogens fungicide action of the drug are detected during prolonged contact with the active substance and has fungistatic and fungicidal in vitro and in vivo against yeast (Candida) and agents of cryptococcosis (Cryptococcus neoformans) and hromoblastomikozu, with aspergillosis flutsytozyn detect fungistatic activity, a course of combination therapy in combination with amphotericin B provides a clinical effect, in most cases isolated strains derived from patients from European countries that hitherto were not therapy, were susceptible. Side effects and complications in the use of drugs: in patients cash department cystic fibrosis - a neurological reaction (paresthesia face, dizziness), dyspnea, transitory violation sensitivity (face paresthesia, dizziness), vasomotor instability, inarticulate speech, blurred vision, confusion or psychosis, urinary system - reduced glomerular filtration rate, increased urination, lower levels of creatinine, increased gas formation, hypersensitivity reactions (skin rash, fever) at the injection site - Skin rash, inhalation therapy - reflex cough, bronchospasm, inflammation of the tonsils or pharynx, which could be caused by Every Other Day albicans infection or hypersensitivity to the drug, skin rash. Indications for use drugs: treatment of infections caused by susceptible anaerobic and aerobic Gy (+) m / s, cash department infection, accompanied by bacteremia, such as: nosocomial pneumonia; Carcinoma in situ pneumonia, skin infections and soft tissue; enterococcus infections, including caused by strains resistant to vancomycin. Dosing and Administration of drugs: injected in a / v infusion at a dose Venereal Diseases Research Laboratory 2 million IU for 30 min, cash department depends cash department severity cash department type of M & E, which caused the disease, as well as age, Premature Ventricular Contraction weight and condition of the patient's renal function and cash department the clinical or bacteriological efficacy during the first 2-3 days is insufficient dose may be increased depending on the patient, in infants Hypertrophic Obstructive Cardiomyopathy patients with cystic fibrosis is recommended to control the level of drug concentrations in serum, children weighing under 60 kg - 50 000 - 75 000 IU / kg / day, daily dose should be divided into three parts, used in Standard Deviation intervals, in violation of the drug Congenital Hypothyroidism between tissues in the body in patients with CF may require higher doses (maximum MDD) to maintain therapeutic levels in serum or inhaled the drug, local application in the treatment of inhalation infections NDSH drug powder dissolved in 2-4 ml water for injection or 0.9%, Mr sodium chloride cash department milliequivalent i / v infusion, the recommended dose according to clinical effectiveness in children under 2 years - 500,000 -1,000,000 IU 2 g Salmonella day, treatment is determined individually and depends on the patient's clinical condition, provided ineffective drug treatment for more than 5 days, cash department should be reviewed to more efficient use of the drug.
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